M1CR0B1AL1Z3R is a webserver for analyzing bacterial genomics data. It gets as input a dataset of bacterial genomes (up to 2120 genomes - the largest dataset size we support) and generates quantitative and qualitative measurements, visual and textual results, ready for publication or further analysis. Some of the outputs are open reading frames of each genome, orthologous groups (both unaligned and aligned), core proteome, phylogenetic tree, KEGG annotation and more. See an example for outputs of a 41-genomes dataset (40 Chlamydia and 1 outgroup) here, and walk-through of the results here.
When citing M1CR0B1AL1Z3R please refer to:
M1CR0B1AL1Z3R 2.0: an enhanced web server for comparative analysis of bacterial genomes at scale
Yair Shimony, Edo Dotan, Elya Wygoda, Naama Wagner, Iris Lyubman, Noa Ecker, Gianna Durante, Gal Mishan, Jeff H Chang, Oren Avram, Tal Pupko
Nucleic Acids Research 2025 | https://doi.org/10.1093/nar/gkaf413.
M1CR0B1AL1Z3R - a user-friendly web server for the analysis of large-scale microbial genomics data
Oren Avram, Dana Rapoport, Shir Portugez, Tal Pupko
Nucleic Acids Research 2019 | https://doi.org/10.1093/nar/gkz423.
The source code of the algorithmic pipeline is available at: https://github.com/orenavram/microbializer
Copyright (C) 2018 Tal Pupko. This program is a free software: you can redistribute it and/or modify it under the terms of the GNU General Public License as published by the Free Software Foundation, either version 2 of the License, or (at your option) any later version. This program is distributed in the hope that it will be useful, but WITHOUT ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU General Public License for more details: https://www.gnu.org/licenses/old-licenses/gpl-2.0.en.html.
For more information, or any other inquiries, please contact yairshimony@mail.tau.ac.il